TCR Vβ repertoire analysis of PBMCs from asymptomatic donors during acute and persistent infection.

Depicted are those Vβ values of the 1 to 25 known families who demonstrated a 2-fold magnitude change (see “Materials and methods”). Expansions that were statistically significant (P < .05) are indicated by an asterisk. Profiles are displayed of fluorescence intensity (x-axis, arbitrary units) as a function of CDR3 size (y-axis, amino acids). All CDR3 peaks are spaced 3 nucleotides apart.