Effect of the inhibition of tissue factor on the clotting time in plasma from 4 patients with severe hemophilia A at different rFVIIa concentrations.

Clotting times were determined using the same conditions as used for the clot lysis assay in the absence (open circles) or presence (closed circles) of a polyclonal inhibitory antibody against tissue factor. Error bars indicate SD. Asterisk indicates P < .05.