Fig. 5.
Effect of TFPI on antifibrinolytic and procoagulant potential of rFVIIa.
(A) Clys½-VIIa values of the 17 plasma samples as shown in Figure 2A (no additions), and Clys½-VIIa values of the same samples in the presence of 100 ng/mL rFL-TFPI (+ TFPI), or an inhibitory antibody against TFPI (+ α-TFPI). (B) Cclot½-VIIa values of the 17 plasma samples as shown in Figure 2B (no additions), and Cclot½-VIIa values of the same samples in the presence of 100 ng/mL rFL-TFPI (+ TFPI), or an inhibitory antibody against TFPI (+ α-TFPI).