Fig. 6.
Correlation of HTLV-1 Tax-specific CD8+ T-cell frequency with HTLV-1 tax mRNA load.
The frequency of HTLV-1 Tax 11-19/HLA-A*0201-specific CD8+ T cells (expressed as a percentage of total CD8+ T cells) was analyzed using a PE-conjugated HLA-A*0201 tetramer for HLA-A*0201 subjects. A significant correlation (P = .0013, r2 = 0.893) was demonstrated between HTLV-1 tax mRNA load and the frequency of HTLV-1 Tax-specific CD8+ T cells in HAM/TSP patients.