Fig. 7.
Effect of medium conditioned by NK cells stimulated with IL-2 (NKCM) on the polyploidy of megakaryocytes derived from blood CD34+ cells stimulated with IL-3 and SCF.
IL-2 by itself had no effect. The activity in the NKCM that induced endomitosis was abolished by pretreatment of NKCM with trypsin immobilized to agarose. Each point represents the mean ± SEM from triplicate cultures of 3 experiments.