Effect of increasing concentration of medium conditioned by NK cells stimulated with IL-2 (NKCM) on the number of polyploid megakaryocytes (more than 4N) generated in vitro from blood CD34⁺ cells stimulated with IL-3 and SCF.

Hatched line represents the range of polyploid megakaryocytes generated in the absence of NKCM. Each point represents the mean ± SEM of quadruplicate cultures in 3 experiments.