Fig. 3.
Effects of ET-1 on K+ influx in normal and sickle erythrocytes in physiological conditions.
Erythrocytes were incubated with and without 300 nM ET-1 for 30 minutes at 37°C in physiological saline medium containing 1.5 mM CaCl2 and 10 μCi/mL (0.37 MBq/mL)86Rb+. K+ uptake was measured at 3 different time points. The slope of the linear curve represents the K+ influx for each condition (300 nM ET-1). Values are expressed as mean ± SE of 3 experiments in duplicate. *P < .04; βP < .03.
