Fig. 4.
SIVenv- and SIVgag/pol-specific CD8+ pCTL frequencies in PBMC samples from rhesus macaques following SIVmac239 infection.
SIV infection alone (A); SIV infection and a 28-day course of PMPA chemotherapy (B); SIV infection, PMPA chemotherapy, and infusions with autologous unfractionated PBMCs (C); SIV infection, PMPA chemotherapy, and infusions with anti-CD3/CD28-stimulated and -expanded autologous CD4+ T cells (D). Sequential Flu-MP–specific CD8+ pCTL frequencies in PBMC samples following SIVmac239 infection alone (E); SIV infection, PMPA chemotherapy, and infusions with autologous unfractionated PBMCs (F); SIV infection, PMPA chemotherapy, and infusions with anti-CD3/CD28-stimulated and -expanded autologous CD4+ T cells (G).