Fig. 1.
![Fig. 1. ATP-triggered lymphocyte [Ca++] increase. / ATP triggers a higher [Ca++]iincrease in lymphocytes from evolutive (A) compared with indolent (B) B-CLL. Lymphocytes were isolated as described in “Study design” and resuspended in Ca++-supplemented or Ca++-free solution at a concentration of 2 × 106/mL. The Ca++-free solution also contained 500 μM EGTA. ATP and ionomycin (iono) were 1 mM and 1 μM, respectively.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/99/2/10.1182_blood.v99.2.706/6/h80221988001.jpeg?Expires=1735824983&Signature=pf0ZOqN3rPEJAgHHNZW7W9AaRZa5Rn0c7nZSfJtIdw1Bhphbo6ZUY2uqUAcNRSXRXjwZ9xvyyj73TkKTX6cjZSR4yCnIqQ3Y1lvdWkmWsOk9bL0u6OdCapqWunlTcQhQwN-1YBFmukCGAnohs98CZWn01iY60uqzhZibDJTY2Mj04NtWzdBnsKHouNOiP3gYOdqQubPPEZTQRxHWwr1FjpXkENc4qnzXwPfNJNY4WKHr6A4I6QzmaPqmNS5ZFMBEW-g22h211HKHf~ngngNbyu5mK2nRMggE2QwcyqaJoQSoGem6zCFe9sCYLUP2M9SpYWet-ILmoqRJriPlavDmCg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
ATP-triggered lymphocyte [Ca++] increase.
ATP triggers a higher [Ca++]iincrease in lymphocytes from evolutive (A) compared with indolent (B) B-CLL. Lymphocytes were isolated as described in “Study design” and resuspended in Ca++-supplemented or Ca++-free solution at a concentration of 2 × 106/mL. The Ca++-free solution also contained 500 μM EGTA. ATP and ionomycin (iono) were 1 mM and 1 μM, respectively.
