Fig. 3.
Fig. 3. Thrombin generation in synthetic blood coagulation model in the absence of factor VIII. / Thrombin generation on 2 × 108/mL platelets was initiated by 25 pM TF in the presence of factors V, VIII, VII, VIIa, IX, and X, prothrombin, AT-III, and TFPI at physiologic concentrations (▪) or in the absence of factor VIII and the presence of 0.1 (○), 5 (▴), 10 (♦), and 40 nM (■) factor VIIa.

Thrombin generation in synthetic blood coagulation model in the absence of factor VIII.

Thrombin generation on 2 × 108/mL platelets was initiated by 25 pM TF in the presence of factors V, VIII, VII, VIIa, IX, and X, prothrombin, AT-III, and TFPI at physiologic concentrations (▪) or in the absence of factor VIII and the presence of 0.1 (○), 5 (▴), 10 (♦), and 40 nM (■) factor VIIa.

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