Fig. 6.
Enhanced rolling of leukocytes in cutaneous blood vessels of TSP-2–deficient mice.
Immunofluorescent stains for CD31 (red) and P-selectin (green) demonstrated increased P-selectin expression in cutaneous blood vessels (yellow) of TSP-2–deficient mice (B), as compared with wild-type mice (A). Scale bars = 100 μm. (C) Intravital microscopy revealed that the rolling fraction of leukocytes in cutaneous blood vessels of TSP-2–deficient mice (▪) was increased by 39.6% over wild-type mice (■). Data are expressed as mean ± SD. ***P < .001.