Platelet counts over time.

Each small number represents a value from one patient identified by number in Table 1. The bars indicate the time of CyA administration. The first 4 numbers represent a follow-up update for the 4 patients described previously.15 In patient 1, CyA treatment was resumed at 20 months because of development of an autoimmune hemolytic anemia. Patient 10 had a relapse at 4 years, with her condition becoming resistant to CyA. The decrease in platelet values in patient 3 occurred concomitantly with administration of felodipine. Patient 8 died of a myocardial infarction during a 3-month course of CyA therapy.