Human IgGs do not affect human RBC survival in NOD-scid mice.

Groups of 3 NOD-scid mice were injected with (○) or without (●) 10 mg human IgGs 18 hours before injection of a volume of 100 μL containing 5 μL ⁵¹Cr-labeled Rh D⁺ RBCs and 35 μL unlabeled Rh D⁻ RBCs in saline. At the indicated times, the amount of circulating ⁵¹Cr-labeled RBCs was determined as described in “Materials and methods.”