Dose-response of anti-D used individually or in a blend.

Groups of 3 NOD-scid mice were injected with human IgGs only (○), or in the presence of 5μg polyclonal anti-D (■), or the following amounts of the indicated monoclonal anti-D: (A) 1 μg 26C1 (▪), 5 μg 26C1 (●), and 10 μg 26C1 (▴); (B) 5μg 19A5 (▪), 10 μg 19A5 (●), and 20 μg 19A5 (▴); and (C) 5 μg of blend (●) and 10 μg blend (▪). The blend was made of equal proportions of 26C1, 46E7, and 25F5. RBCs were prepared and injected as in Figure1.