Fig. 5.
Fig. 5. Cytologic evaluation of APL cells from PML-RARα Gly289Arg mutant case 6 in the absence or presence of RA or NaB alone and in combination. / Photographs of cytospin slide preparations of sodium metrizoate–selected low-density (P ≤ 1.077 g/mL) bone marrow cells were taken at × 1000 magnification of modified Wright stain (Dif-Quik, Sigma, St Louis, MO). (A) Prior to culture; (B-E) cultured × 4 days with (B) no added drug, (C) 1 μM RA, (D) 1 mM NaB, or (E) 1 μM RA + 1 mM NaB.

Cytologic evaluation of APL cells from PML-RARα Gly289Arg mutant case 6 in the absence or presence of RA or NaB alone and in combination.

Photographs of cytospin slide preparations of sodium metrizoate–selected low-density (P ≤ 1.077 g/mL) bone marrow cells were taken at × 1000 magnification of modified Wright stain (Dif-Quik, Sigma, St Louis, MO). (A) Prior to culture; (B-E) cultured × 4 days with (B) no added drug, (C) 1 μM RA, (D) 1 mM NaB, or (E) 1 μM RA + 1 mM NaB.

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