Fig. 1.
Fig. 1. Evidence for cooperation between As2O3 and cAMP signaling pathways. / Morphologic features of NB4 (A) and NB4-R1 (B) cells after a 96-hour exposure to the drugs indicated. Original magnification × 1000. Expression of CD11b integrin and NBT-reducing activity of NB4 (C,E) and NB4-R1 cells (D,F) following the indicated treatments. Inhibitory effect of H89 on CD11b expression (G) and NBT activity (H) in NB4 and NB4-R1 cells treated by the indicated drugs for 5 and 4 days, respectively, is shown. Each value represented the mean ± SD of 3 independent measurements.

Evidence for cooperation between As2O3 and cAMP signaling pathways.

Morphologic features of NB4 (A) and NB4-R1 (B) cells after a 96-hour exposure to the drugs indicated. Original magnification × 1000. Expression of CD11b integrin and NBT-reducing activity of NB4 (C,E) and NB4-R1 cells (D,F) following the indicated treatments. Inhibitory effect of H89 on CD11b expression (G) and NBT activity (H) in NB4 and NB4-R1 cells treated by the indicated drugs for 5 and 4 days, respectively, is shown. Each value represented the mean ± SD of 3 independent measurements.

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