Fig. 1.
p14ARF expression in lymphoid cell lines.
(A) Multiplex PCR demonstrating deletion of p14ARF exon 2 in some of the cell lines. p53 exon 8 is simultaneously amplified as a control. (B) Images showing absence of p14ARF staining in 2 cell lines with exon 2 deletion (MOLT-4, GRANTA-519) and nucleolar p14ARF expression in 2 nondeleted cell lines (NAMALWA, RPMI 8226). Note the nucleoplasmic staining for RPMI 8226 observed in addition to the nucleoli. Original magnification × 1000.