Fig. 7.
Effect of DSP30 on sensitivity to LMB-2 of normal lymphocytes.
Human tonsillar B cells (A) and T cells from peripheral blood of healthy donors (B) were isolated as described in the text and in the legend to Figure 6. 3 × 105 T lymphocytes and tonsillar B cells were cultured with or without DSP30 in the presence of indicated concentrations of LMB-2 (♦) or LMB-9 (■). Cell viability was determined with an MTS assay after 5 days as described in the text. Human tonsillar B cells cultured in medium alone were measured after 3 days. Shown are representative experiments; 2 additional experiments gave similar results.