Fig. 6.
Time course of cdk4 kinase activity inhibition.
Indicated cells were grown to subconfluence, harvested by centrifugation, and replated for indicated times in the presence of DMSO (0.1%), alone, LY294002 (25 μM), or STI571 (1 μM). Cells were harvested and cdk4 kinase assays performed as in Figure 5.