Dose-response curves of retrovirally transduced rat leukemic cell lines.

Metabolic activities of the cells in the presence of increasing concentrations of AraC for 72 hours was analyzed by the cell proliferation assay WST-1. Y-axis (fraction control) represents the metabolic activity of the cells in the presence of AraC divided by the metabolic activity of cells grown in the absence of AraC. (A) Retrovirally transduced KA cells. (B) Retrovirally transduced K7 cells. (♦) untransduced control cells; (▪) cells transduced with empty vectors; (▴) cells transduced with wt dCK; (○) cells with deletion exon 5 dCK; (▵) cells with deletion exons 3 to 4 dCK; (■) cells with deletion exons 3 to 6.