Fig. 5.
SOCS-2 expression in primary CML blast cells.
Real-time RT-PCR for SOCS-2 of cDNA samples from patients with CML in CP or BC or from healthy individuals. Results have been normalized by comparison to their GAPDH mRNA expression. (A) cDNA samples from patients with CML in CP or BC and from healthy individuals. (B) cDNA samples from 4 patients with CML in BC during treatment with STI571. Data are compared with the gene expression levels before initiation of therapy.