IL-18R on T and NK cells.

Splenic nonadherent cells were stained with anti–IL-18R mAb followed by FITC-conjugated antirat IgG1, together with PE-conjugated anti-CD4, anti-CD8, or anti-DX5. The proportion of IL-18R⁺ cells gated among the CD4⁺ (A), CD8⁺ (B), or DX5⁺ (C) cells is shown before and after culture with 2 ng/mL IL-12 for the indicated days.