Fig. 5.
Effect of CD40 ligation on the B-cell chemotactic response.
CD38− B cells were precultured for 6 hours in the absence (hatched bars) or in the presence of 10 μg/mL anti-Ig Abs (open bars) or CD40L (black bars) before performing the chemotaxis assay. The concentrations of chemokines used were the same as for Figure 4. Results correspond to the percent specific migration and are expressed as the mean ± SD of experimental duplicates. Representative of 3 separate experiments.