Genealogical trees for the V_H and the V_λ rearrangements of case 3.

There were 11 cells that carried a V_H as well as a V_λ gene amplificate (the names of the cells are given in the trees). In the V_λ tree generated by the software, one mutation (either 200 G to A or 200 G to C in all sequences; see sequences available from the EMBL data library) was erroneously regarded as a shared mutation. This was corrected, defining the mutations as distinct events. Furthermore, we positioned f1-37 into the left main branch of the V_λ tree to get compatibility in the heavy and light chain genealogical trees. Dup indicates duplication. See Figure 2 for additional explanations.