An A/C SNP at position 2108 of the CD109 cDNA defines the Gov alloantigens.

CD109 cDNA sequences flanking nucleotide 2108 and derived from a Gov^aa (top panel) or a Gov^bb (bottom panel) panel 1 donor are shown. Nucleotide coordinates correspond to the CD109 cDNA sequence of Lin et al.10 The nucleotide 2108 SNP is concordant with the Gov phenotyping and results in an amino acid substitution.