Fig. 8.
![Fig. 8. Transduced cells are rescued to proliferate by stimulation with autologous EBV-LCLs. / 14.G2a-ζ–transduced (A) and nontransduced (B) EBV-specific CTLs were stimulated with irradiated autologous (Auto) or mismatched allogeneic (Allo) LCLs, or with GD2+ (LAN-1) or GD2− (A-204) tumor cells at a 1:4 stimulator-to-responder ratio. After 7 to 14 days, CTLs were stimulated with autologous LCLs (Auto/Auto, LAN-1/Auto, JF/Auto, A-204/Auto, Allo/Auto) or stimulated as before (LAN-1/LAN-1, JF/JF, A-204/A-204, Allo/Allo). Proliferative responses were then assessed by measurement of [3H]-thymidine uptake. Shown is a representative experiment of 2.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/99/6/10.1182_blood.v99.6.2009/6/h80622263008.jpeg?Expires=1735848204&Signature=fN5yKPXJADMixKbB9NkYCMhpNbB5AyaOtKqj-ffDSBROLsodRTF5A6F094VRaBctwHmFBcmL0abIP3xE8YudTln1rufUZ8Q2JuoAZxMFkvrq1iAL2nvwFC59jnbwq56mbqwSr7d2dWwTvh-q8x0yewpH5LAJFEDq63QkMF4NN0UFzMBbhozoVn-a7T4QWGd9ckDKZl6zQX7ue-3m~s5NLcKyYtAjY9d77r~8-NFhHHd6GCKyRxX9VZ7t5VVTJrT8iJ0yYeYZSUoUJX7xEA-vJDnfp7WqqJjY7HygCI42KRWdAf2CXupJFEmQ1KaFP8IzSjE0hUZc5qImxWoImfM3wQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Transduced cells are rescued to proliferate by stimulation with autologous EBV-LCLs.
14.G2a-ζ–transduced (A) and nontransduced (B) EBV-specific CTLs were stimulated with irradiated autologous (Auto) or mismatched allogeneic (Allo) LCLs, or with G (LAN-1) or G (A-204) tumor cells at a 1:4 stimulator-to-responder ratio. After 7 to 14 days, CTLs were stimulated with autologous LCLs (Auto/Auto, LAN-1/Auto, JF/Auto, A-204/Auto, Allo/Auto) or stimulated as before (LAN-1/LAN-1, JF/JF, A-204/A-204, Allo/Allo). Proliferative responses were then assessed by measurement of [3H]-thymidine uptake. Shown is a representative experiment of 2.
