Reactions of serum from 104 unselected healthy subjects against abciximab-coated platelets.

Values shown are MFI values obtained with abciximab-coated platelets minus the MFI obtained with uncoated platelets. A difference of 5.0 MFI units or more, indicating that the signal against abciximab-coated platelets was at least twice that obtained with uncoated platelets, was considered indicative of significant binding of IgG to the sensitized platelets. By this criterion, antibodies were present in 77 subjects (74%).