Fig. 2. Longitudinal data of... | American Society of Hematology

Fig. 2.

$Fig. 2. Longitudinal data of HIV-infected individuals during the course of infection. / Months are given from time of seroconversion, AIDS diagnosis is indicated with arrows on the x-axes, and HAART, dual therapy, or monotherapy is indicated with dotted lines and defined in Table 1. Upper panels show CD4+ (▪) and CD8+ (♦) T-cell numbers and viral RNA copies per milliliter serum (thick lines). Middle panels indicate absolute numbers of tetramer+ T cells (●) and IFN-γ–producing T cells (○). HLA restrictions and dominant peptide responses are indicated by the first 3 amino acids of the peptides described in “Patients, materials, and methods.” The IFN-γ+ fraction of tetramer+ T cells is plotted in the lower panels (▵). Results of replicate measurements are indicated in the lower panels (▴).$

Longitudinal data of HIV-infected individuals during the course of infection.

Months are given from time of seroconversion, AIDS diagnosis is indicated with arrows on the x-axes, and HAART, dual therapy, or monotherapy is indicated with dotted lines and defined in Table 1. Upper panels show CD4⁺ (▪) and CD8⁺ (♦) T-cell numbers and viral RNA copies per milliliter serum (thick lines). Middle panels indicate absolute numbers of tetramer⁺ T cells (●) and IFN-γ–producing T cells (○). HLA restrictions and dominant peptide responses are indicated by the first 3 amino acids of the peptides described in “Patients, materials, and methods.” The IFN-γ⁺ fraction of tetramer⁺ T cells is plotted in the lower panels (▵). Results of replicate measurements are indicated in the lower panels (▴).

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