Fig. 6.
Correlations between HIV-specific T cells CD4+ T cells IFN-γ+ T cells and IFN-γ+ fractions.
All time points of all subjects are included in each plot. Filled symbols indicate progressors (n = 11); open symbols, asymptomatics (n = 5). HLA restrictions are indicated. (A) Absolute numbers of tetramer+ T cells do not correlate with CD4+T-cell counts. (B) Absolute numbers of IFN-γ–producing CD8+ T cells correlate with absolute numbers of tetramer+ T cells. (C) Absolute numbers of IFN-γ–producing CD8+ T cells correlate with absolute numbers of CD4+ T cells. (D) IFN-γ+percentage of tetramer+ T cells correlates with CD4+ T cell counts.