Fig. 2.
UT-7/9 expressing high level of BCR-ABL overexpress ICAM-1.
UT-7 parental cells and transfectants UT-7/E8.1 and UT-7/9 were labeled with anti–HLA-I (W6/32), anti–ICAM-1 (CD54), anti–LFA-1 (CD11a), and LFA-3 (CD58), shown by bold lines. MFI indicates mean fluorescence intensity values. (B) Cytotoxic activity of dNK cells toward UT-7 (left panel) and UT-7/9 cells (right panel) in the presence or absence of anti–ICAM-1 or irrelevant anti-CD4 mAbs. One representative experiment of 3 is shown.