The effect of pretreatment with colchicine on the apparent stiffness of quiescent neutrophils or neutrophils stimulated with fMLP.

Pretreatment of neutrophils with colchicine (50 μM) did not alter the apparent stiffness of quiescent neutrophils isolated from either the BM or the circulating blood. Colchicine also did not prevent the increase in stiffness induced by fMLP. n = 5 rats in each group. BM indicates bone marrow; C, circulating.