Analysis of the activity of IL-17 on CTL effector capacity.

We selected CTLs specific for P815 A-E− and compared their cytolytic activity with that of parent P815 A-E− cells or IL-17–producing P815 A-E− tumor cells. The target cells were labeled with chromium and incubated at a constant density with CTLs specific for anti-P815 A-E− at different effector-to-target ratios.