Concentrations of NGF, but not NT-3, in nasal secretions from patients with allergic rhinitis correlate with EDN concentrations.

Nasal lavage fluids were collected from patients with ragweed hay fever during the peak of the allergy season, as described in detail in “Materials and methods.” Concentrations of NGF, NT-3, and EDN in the cell-free supernatants of lavage fluids were measured by ELISA and RIA. (A) This panel shows the correlation between the EDN and NGF concentrations in the lavage fluids. (B) This panel shows the correlation between the EDN and NT-3 concentrations in the lavage fluids. Each dot represents the data from each patient. Pearson coefficient of correlation and significance of correlation are shown in the lower right corner.