Fig. 1.
Probability of sustained remission according to FC MRD results, relative and absolute estimate, at 4 time points during the first 6 months of ALL therapy.
Probabilities of the RFI were calculated using the method of Kaplan-Meier and were based on individual intervals between a respective MRD assessment and relapse or last observation. SDs of pRFI, 3-year estimates, and comparisons of groups of patients using the log-rank test are also shown. Relative MRD values relate to percentages of leukemic cells among total NCs of the sample, and absolute counts represent leukemic cells per microliter BM.