Plasmablastic lymphoma complicating HIV-associated MCD in patients 12 and 14.

In patient 14, spleen analysis (A) shows a diffuse infiltration with plasmablastic cells, which stained positive with a KSHV/HHV8 specific LNA-1 monoclonal antibody (B). In patient 12, a blood smear (C) shows leukemic plasmablastic cells and nuclear staining of the circulating plasmablastic cells with a KSHV/HHV8 specific LNA-1 monoclonal antibody (D). Original magnification ×400 in panel A; ×100 in panel B; and ×2400 in panels C and D.