Effect of AT supplementation before LPS challenge toAT+/− mice.

Prophylactic AT treatment was performed 4 hours before LPS challenge using 50 U/kg human AT concentrates (AT) as described in “Materials and methods.” The same volume of control physiological saline was injected. AT supplementation significantly reduced %GFD of AT+/− mice (n = 12;P < .05). Values are means ± SD.