Fig. 5.
pDC2 and B cells develop from CD34+ cells independent of a human thymus graft in Rag2−/− γc−/− mice.
Murine peripheral blood (A,E), spleen (B,F), liver (C,G), and bone marrow (D,H) were examined by flow cytometry for the presence of human cells (CD45+) expressing CD3, CD4, CD19, and CD123 16 weeks after intravenous injection of CD34+ fetal liver cells. Immunophenotype is shown of cells expressing human CD45. Isotype control antibodies were used to set the cursors.