The (1-63) bcr/abl mice develop T-ALL.

(A) FACS analysis of peripheral blood from a representative healthy (1-63) bcr/abl mouse at day 40 after BMT. The WBC count was 15 × 10⁶ cells/mL, which is similar to the MigR1 controls. Note the abnormal population of GFP⁺B220⁺CD43⁺cells. (B) FACS analysis of peripheral blood (center) and thymus (right) from an ill (1-63) bcr/abl mouse (no. 2). The WBC count is normal. Note the disappearance of the abnormal pre-B cells from the peripheral blood. The thymic tumor cells were GFP⁺CD4⁺CD8⁺.