Fig. 5.
Fig. 5. Staurosporine blocked thrombin-induced PKC phosphorylation and proteolysis of adducin. / Preincubation of platelets with the kinase inhibitor staurosporine (10 minutes) completely blocked thrombin-induced PKC phosphorylation of adducin (B) and proteolysis (C). Thrombin concentration, 1 U/mL; CaCl2, 2.5 mM.

Staurosporine blocked thrombin-induced PKC phosphorylation and proteolysis of adducin.

Preincubation of platelets with the kinase inhibitor staurosporine (10 minutes) completely blocked thrombin-induced PKC phosphorylation of adducin (B) and proteolysis (C). Thrombin concentration, 1 U/mL; CaCl2, 2.5 mM.

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