Fig. 9.
Platelet aggregation was delayed by staurosporine and inhibited by calpeptin.
Column-purified platelets were stimulated with thrombin (1 U/mL) in the presence of 2.5 mM CaCl2, and the percentage of aggregation was followed as a measure of change in light transmission over 120 seconds. (A) Control, (B) 0.8% DMSO (vehicle), (C) 0.3 μM staurosporine 30 minutes preincubation, (D) 200 μg/mL calpeptin 30 minutes preincubation.