American Society of Hematology

Fig. 6.

$Fig. 6. Lymph node IDCs but not B cells from monkeys with AIDS are refractory to CD40 ligation. / Lymph node cell suspensions were analyzed before or following overnight culture with or without CD40L (3 μg/mL) and stained for expression of CD83 and CD20. The proportions of IDCs (CD83+CD20−, top) and activated B cells (CD83+CD20+, bottom) from freshly isolated lymph nodes (F), or lymph node cells cultured with or without CD40L from healthy monkeys (open squares, n = 3), and monkeys with acute SIV infection (open circles, n = 3) or AIDS (filled triangles, n = 3) are shown. The data represent mean ± SEM.$

Lymph node IDCs but not B cells from monkeys with AIDS are refractory to CD40 ligation.

Lymph node cell suspensions were analyzed before or following overnight culture with or without CD40L (3 μg/mL) and stained for expression of CD83 and CD20. The proportions of IDCs (CD83⁺CD20⁻, top) and activated B cells (CD83⁺CD20⁺, bottom) from freshly isolated lymph nodes (F), or lymph node cells cultured with or without CD40L from healthy monkeys (open squares, n = 3), and monkeys with acute SIV infection (open circles, n = 3) or AIDS (filled triangles, n = 3) are shown. The data represent mean ± SEM.

This Feature Is Available To Subscribers Only