Fig. 2.
IgG3 self-association assay.
Various amounts of 6-19 (○), 6-19N471T (●), and 6-19 IgG1 variant, SS2F8 (▪), were incubated with 125I-labeled 6-19 mAb (10 ng) in the presence of 10 μL normal mouse serum. Results are expressed as a percentage of labeled 6-19 precipitated specifically.