Longitudinal analysis of T-cell recovery, Ki67 expression, TREC content, and number of TRECs in 4 patients.

Naive CD4⁺ T cell numbers (A), CD4⁺ TREC content (B), and the absolute number of TREC⁺CD4⁺ T cells (C) increased over time. Although the kinetics of naive T-cell recovery were different for each patient, those of TREC content and TREC number were similar. Peripheral cell division (D) was associated with clinical events and declined with time. Gray circles in (C) indicate values for healthy controls. In each panel, squares, triangles, and diamonds represent individual patients; symbols with cross-hair indicate infectious complications monitored at that time point (group 2 patients).