Fig. 1.
![Fig. 1. CTCL cells proliferate only in the presence of APCs. / CTCL cells were obtained from 1- (▪) and 3-month (▨) cultures of 2 representative patients and were freed of APCs by CD2–magnetic bead enrichment. The purified CTCL cells were readded after overnight culture to γ-irradiated autologous APCs that had been CTCL cell bead-depleted. After 3 additional days of culture, only CTCL cells cocultivated with APCs proliferated, as shown by uptake of [3H]-thymidine. The results presented are the means of 5 replicate samples ± SD.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/99/8/10.1182_blood.v99.8.2929/4/h80822428001.jpeg?Expires=1735537684&Signature=nQlHYNBJ1ZXZjTuQ6gGSQdeLZVqO0A68SqGc-XeIFsspRcH~FXV36iCds4FenZsFAmojWaMM1mCbqOexWGiFr9mr-810QShm~z~DR7~xARo47XPPQSHjBKa4ebNXKLH894qW-Oi2v0CjmUB4zeri9RXmEp2smsIlt5Kt-Hh9VSxBUDWF0QKfpJqbh74gZDpIRV3iGn5EHR7J13QL8qG1xFUa1TzFBcUTQs7Om4CZh82lHJWlCV35-TBbxRaXNtrY8B9ldzs8RGR0EJOPXlPyyI2csBU-qwNWi0qfk-HbKzGRYFMh~Dj3RPiBri1A3aI8PQDgQqh6XffXC-GNyzkSeg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
CTCL cells proliferate only in the presence of APCs.
CTCL cells were obtained from 1- (▪) and 3-month (▨) cultures of 2 representative patients and were freed of APCs by CD2–magnetic bead enrichment. The purified CTCL cells were readded after overnight culture to γ-irradiated autologous APCs that had been CTCL cell bead-depleted. After 3 additional days of culture, only CTCL cells cocultivated with APCs proliferated, as shown by uptake of [3H]-thymidine. The results presented are the means of 5 replicate samples ± SD.
