Fig. 4.
Flow cytometry phenotype of the APC at 1 and 3 months of culture.
(A-D) At 1 month of culture, the APCs from a representative CTCL patient are a mixture of immature APCs that express costimulatory molecules CD80 (A) and CD86 (B); class II MHC molecules (C); and mature DC that express CD83 (D). (E) By 3 months of culture, the majority of the APCs from a representative patient express higher levels of class II MHC molecules.