Fig. 6.
![Fig. 6. Antibodies that interfere with direct membrane contact of the CTCL cells and the APC block proliferation. / The cocultures were incubated with antibodies to the clonotypic TCR (Vβ5c), CD40 on the APC or an isotype control (IgG1), and proliferation measured by uptake of [3H]-thymidine. Interference with the TCR or the interaction of CD40 with its ligand on the CTCL cells inhibited proliferation. The results represent the mean ± SD of 5 replicate samples.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/99/8/10.1182_blood.v99.8.2929/4/h80822428006.jpeg?Expires=1735535692&Signature=HLqZ5JYv333-55xy3YwdF3TwLPpLTPUVKvO2PDIeJX0lJrBucClIRKrf-RDhJqhcP~8i0SvA74GxjLPuUbqVWESXFFKv8xxiSKvAZd-BmYfD~lTCV8r~43in1Ajy~1XS-xR1E-hbl8bu~dzwkRXlWRjmSv~uhxFUKlhpM-LF~ZRKVNQU~iwQKikS6w2VdplsAd3EpVzzV~SZDakxvk7Y5gQeVBzSbWW0sWoYNvw4OB9g2HlV-FffTGwL-6uq~eMfIObFdFN7~kPB~NthN4frVM40Kye14PGKg59lENQ5ksk~w37TcQfwJpaGEiPgOhmV6a2LrP74wr5MBlcZsR2pXQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Antibodies that interfere with direct membrane contact of the CTCL cells and the APC block proliferation.
The cocultures were incubated with antibodies to the clonotypic TCR (Vβ5c), CD40 on the APC or an isotype control (IgG1), and proliferation measured by uptake of [3H]-thymidine. Interference with the TCR or the interaction of CD40 with its ligand on the CTCL cells inhibited proliferation. The results represent the mean ± SD of 5 replicate samples.
