Fig. 6.
Surface-antigen analyses of BM before and after As4S4 treatment.
Expression of surface antigens of CD33, CD13, and CD15 in BM mononuclear cells was analyzed by flow cytometry before and after As4S4 treatment. Data are mean ± values from 13 patients, 9 with newly diagnosed disease and 4 with relapse. Before treatment, most cells expressed only CD33 and CD13, typical of APL. After HCR was achieved, most myeloid-lineage cells expressed CD15, the antigen usually found on mature cells.
