Fig. 3.
![Fig. 3. Replacement of xenogeneic CD40L transfectants with recombinant, trimeric, soluble CD40L. / The generation of CD40–B cells was studied by means of CD40L-transfected NIH3T3 cells (panel A) or GMP-grade soluble trimeric CD40L (panel B) under varying concentrations of clinical-grade rhIL-4 (shown here: 0 [filled circles], 2 [filled squares], and 10 [filled diamonds] ng/mL). A representative experiment of 3 experiments is shown.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/99/9/10.1182_blood.v99.9.3319/6/h80922505003.jpeg?Expires=1735602655&Signature=SXYWx5wRyWNrDY7fbRrE~OCquJ6M2UhUXyABglLYReO-DEdjT6aj1p6jVGr0vzE0opF0zKKMnoBnq8gKPnfpWn-Ab4zEm3BIgyTV2URZ9aaKyW2xm2LwIaeU6IthaerNxE3qVAic8RBq-yHDgc2BV1cU06BZ4BWVhUiRQUqoiUx2tcoBALiwAW2VSdks3nq2Vh6YEr-5o6jQ7G0KXKMfaoUrsDU7oJuCEf51BMnzUDef7Q1uK6KlkxEzDjbSifKDr5ZPWuhW5sHJTbT2jVPyXQClV-AVd7rDDNj5nu8U3nWwdfznp03F6yLJ3HAFpIi30t1DWdRw4Zsbslg2ZFaTxQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Replacement of xenogeneic CD40L transfectants with recombinant, trimeric, soluble CD40L.
The generation of CD40–B cells was studied by means of CD40L-transfected NIH3T3 cells (panel A) or GMP-grade soluble trimeric CD40L (panel B) under varying concentrations of clinical-grade rhIL-4 (shown here: 0 [filled circles], 2 [filled squares], and 10 [filled diamonds] ng/mL). A representative experiment of 3 experiments is shown.
