Fig. 9.
HATGF-βRII-Δcyt–transduced CTLs will fail to proliferate in the absence of IL-2 or LCL stimulation.
The proliferation of long-term HATGF-βRII-Δcyt–transduced CTL (gray) and nontransduced CTL lines (black) were determined by3[H]thymidine uptake. The3[H]thymidine uptake of CTL lines left in culture for 4 weeks after transduction and stimulated weekly with LCL and IL-2 were compared with the same CTL lines grown in the absence of LCL/IL-2 stimulation for 3 weeks.