Deduced protein sequences of scFv that bind to the C2 domain.

Sequence numbering is according to Kabat et al.26Sequences are available from GenBank under accession numbers AY050689(VHWR1), AY050690 (VHWR10), AY050691 (VLWR10), AY050692 (WR11),AY050693 (VLWR11), AY050694 (VHWR13), AY050695 (VHWR14), AY050696(VHWR15), AY050697 (VLWR15), AY050698 (VHWR16), AY050699 (VLWR16),AY050700 (VHWR17), AY050701 (VLWR17), AY050702 (VHWR19), AY050703(VLWR1), AY050704 (VHWR2), AY050705 (VHWR20), AY050706 (VHWR3),AY050707 (VLWR3), AY050708 (VHWR7), AY050709 (VHWR8), AY050710(VLWR10), AY050711 (VHWR9), and AY050712 (VLWR9). FR indicates framework region; dashes, sequence identity to germline. Amino acid substitutions most likely introduced by the use of V_H gene family–specific oligonucleotide primers during amplification of V_H repertoires are indicated in lowercase.